Background: Minimizing the overall treatment time is an issue of great importance in cancer management.Concomitant boost is a way of decreasing the overall treatment time in breast cancer.The present prospective randomized study aimed to evaluate the feasibility and toxicity and cosmetic outcome of concomitant weekly boost in patients with breast c
Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription
Summary: The ARID1A subunit of SWI/SNF chromatin remodeling complexes is a potent tumor suppressor.Here, a degron is applied to detect rapid loss of Gas Oven Thermostat chromatin accessibility at thousands of loci where ARID1A acts to generate accessible minidomains of nucleosomes.Loss of ARID1A also results in the redistribution of the coactivator
Exterior Noise Due to Interaction of Tire-Thermoplastic Transverse Rumble Strips
Transverse rumble strips (TRS) are a common choice to reduce vehicle speed and increase driver alertness on roadways.However, there is a License Plate Frames potential trade-off using them on rural roadway due to the noise problem created when vehicles go over the strips.The present study investigated the noise level, spectral analysis and the poss